Weight loss / GLP-1
Zepbound cost with insurance.
Zepbound (tirzepatide) costs $25–$455/month for most insured patients depending on plan tier and deductible status, with prior authorization typically required and LillyDirect self-pay available at $349/month for eligible commercial-plan patients.
Sample data — not yet verifiedPrior auth requiredTier 3
$1,086
List price (1 month)
$549
Cash discount
$349
LillyDirect self-pay
Related medications
See how Zepbound compares
FAQ
Zepbound cost questions
Why is Zepbound so expensive?
Zepbound is a brand-name weight loss / glp-1 medication, list price ~$1086/month, because it's still under patent — generics aren't yet available. Insurance can bring this down significantly once your deductible is met.
Does insurance cover it?
Most major insurance plans cover Zepbound as a Tier 3 drug, though prior authorization is typically required. Coverage varies by plan — use the calculator above for a plan-specific estimate.
Is there a generic for Zepbound?
No generic for tirzepatide is currently FDA-approved. The closest cost-saving options are manufacturer self-pay programs like LillyDirect Self-Pay, which can drop the price to around $349/month for eligible patients.
What if my insurance denies it?
If your prior authorization is denied, options include: appealing with your prescriber, switching to a similar covered drug in the same therapeutic class, or using the manufacturer's self-pay program. The calculator above shows all four payment paths.
Data sources
Source URLs for Zepbound have not yet been verified. Estimates below are modeled from general public pricing patterns.
- • Manufacturer published pricing pages
- • NADAC National Average Drug Acquisition Cost
- • Carrier-published formulary tiers (where known)
- • Cost Plus Drugs / mail-order public pricing
- • FDA Orange Book (generic availability)